Background/Aims Two-dimensional shear-wave (2D-SWE) elastography is among the noninvasive methods for the evaluation of liver fibrosis. and sustained viral response (SVR) had the same rate of 99.2% (130/131). The SWE measurement (mean) values at pretreatment, EOT, and 12 weeks after treatment was 12.92, 10.45, and 9.07 kPa, respectively (p 0.05), whereas the APRI scores were 0.76, 0.39, and 0.30, respectively (p 0.05). Additionally, the FIB-4 scores at pretreatment, EOT, and 12 weeks after treatment were 2.98, 2.43, and 2.03, respectively (p 0.05). The results of liver stiffness measurements (LSM) were similar in all the groups of cirrhotic, noncirrhotic, treatment-experienced, and treatment-naive patients. Conclusion DAA treatments in the patients with CHC led to almost a complete SVR and a considerable decrease in LS in a short time. Ethics committee approval was received for this study from the Ethical Committee of Mersin University (decision date: 07/02/2019. desicion number: 78017789/050.01.04/E970387). Written educated consent was from the patients who participated with this scholarly research. Externally peer-reviewed. Concept C O.S., S.Con.; Style C O.S., S.Con.; Guidance – E.A., O.S.; Source C O.S., S.Con., O.?.; Components CO.S., E.A., E.U., O.?., E.A., E..; Data Collection and/or Control C O.S, E.A., E.A., E.., S.Con., O.?.; Evaluation and/or Interpretation C S.Con., O.S.; Books Search C O.?., E.., E.A.; Composing C S.Con., O.S.; Important Evaluations C O.S. Zero conflict is had from the writers appealing to declare. The authors announced that scholarly study has received no financial support. Sources 1. Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C pathogen disease. Lancet Infect Dis. 2005;5:558C67. doi: 10.1016/S1473-3099(05)70216-4. [PubMed] [CrossRef] [Google Scholar] 2. Barr RG, Ferraioli G, Palmeri ML, et al. Elastography Evaluation of Liver organ Fibrosis: Culture of Radiologists in Ultrasound Consensus Meeting Declaration. Radiology. 2015;276:845C61. doi: 10.1148/radiol.2015150619. [PubMed] [CrossRef] [Google Scholar] 3. Gebo KA, Herlong HF, Torbenson MS, et al. Part of liver organ biopsy in general management of persistent hepatitis C: a organized review. Hepatology. 2002;36(5 Suppl 1):S161C72. doi: 10.1053/jhep.2002.36989. [PubMed] [CrossRef] [Google Scholar] 4. Marcellin P, Asselah T, Boyer N. Disease and Fibrosis development purchase Sotrastaurin in hepatitis C. Hepatology. 2002;36(5 Suppl 1):S47C56. doi: 10.1002/hep.1840360707. [PubMed] [CrossRef] [Google Scholar] 5. Abe T, Kuroda H, Fujiwara Y, et al. Precision of 2D shear purchase Sotrastaurin influx elastography in the analysis of liver organ fibrosis purchase Sotrastaurin in individuals with persistent hepatitis C. J Clin Ultrasound. 2018;46:319C27. doi: 10.1002/jcu.22592. [PubMed] [CrossRef] [Google Scholar] 6. Ishak K, Baptista A, Bianchi L, et al. Histological staging and Rabbit Polyclonal to CROT grading of persistent hepatitis. J Hepatol. 1995;22:696C9. doi: 10.1016/0168-8278(95)80226-6. [PubMed] [CrossRef] [Google Scholar] 7. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of persistent hepatitis: diagnosis, staging and grading. Hepatology. 1994;19:1513C20. doi: 10.1002/hep.1840190629. [PubMed] [CrossRef] [Google Scholar] 8. Sheth SG, Flamm SL, Gordon FD, Chopra S. AST/ALT percentage predicts cirrhosis in individuals with chronic hepatitis C virus contamination. Am J Gastroenterol. 1998;93:44C8. doi: 10.1111/j.1572-0241.1998.044_c.x. [PubMed] [CrossRef] [Google Scholar] 9. Kim BK, Kim DY, Park JY, et al. Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients. Liver Int. 2010;30:546C53. doi: 10.1111/j.1478-3231.2009.02192.x. [PubMed] [CrossRef] [Google Scholar] 10. Bert F, Stahmeyer JT, Rossol S. Ultrasound Elastography Used for Preventive noninvasive Screening in Early Detection of Liver Fibrosis. J Clin Med Res. 2016;8:650C5. doi: 10.14740/jocmr2625w. [PMC free article] [PubMed] [CrossRef] [Google Scholar] 11. Dietrich CF, Bamber J, Berzigotti A, et al. EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long.

Background/Aims Two-dimensional shear-wave (2D-SWE) elastography is among the noninvasive methods for the evaluation of liver fibrosis