The framework for the elimination of mother-to-child transmission (EMTCT Plus) was proposed by the Pan American Health Business in 2017 to all member states in order to widen the already existing framework for HIV and syphilis to include elimination of the infection with hepatitis B virus (HBV) and Chagas disease (ChD), now called EMTCT Plus. like the Tri-Border Area between Argentina, Bolivia, and Paraguay located in the Gran Chaco region. Moreover, this region is usually a hotspot for neglected tropical diseases [2], not only for intestinal helminth infections but also for ChD [3]. This is the Levobupivacaine area that will be used as an example in the current tutorial to aid others in the implementation of the framework. For this purpose, we have posed a series of statements that aim to describe the different components, based on our experience, that should be considered for implementation of this framework. Aims of the EMTCT Plus framework for the Region of the Americas Reduction of the rate of MTCT of HIV to 2% or less Reduction of the incidence of MTCT of syphilis (including stillbirths) to 0.5 cases or less per 1,000 live births Reduction of hepatitis B antigen (HBsAg) prevalence among 4- to 6-year-old children to 0.1% or less More than 90% of children cured of Chagas infection with posttreatment negative serology. The prevention of MTCT of the infections included in the EMTCT Plus framework requires the application of different interventions directed specifically to women and their newborns before pregnancy and during pregnancy as well as after childbirth. Accordingly, a program for such an area needs to be designed bearing in mind the socioeconomic and environmental characteristics of the communities and centered on pregnant women and maternal-child health with a special focus on the opportunity of access to quality healthcare, the harmonization between the Levobupivacaine different levels of capacity of the health systems of the area, the concept of equity in access to health, and, ultimately, the strengthening of the healthcare capacities in the area in order to reach the proposed seeks of EMTCT Plus (specific objectives are outlined in Package 1). Since gender equality is definitely a concept totally inherent to the context of the EMTCT Plus platform, the system needs to adhere to recommendations, norms, and methods related to sexual and reproductive health rights, womens rights, and the health of their children. Box 1. Example of specific aims and objectives that can be formulated for any tailor-made system within the objectives of the EMTCT Plus platform: The case of the Tri-Border Area between Argentina, Bolivia, and Paraguay General system objective Collaborate in the implementation of the EMTCT Plus platform in a geographical delimitated area of the Tri-Border Area between Argentina, Bolivia, and Paraguay in the Gran Chaco region together with the local, regional, and national health systems of each country in order to improve local capacity and promote access to high quality healthcare practices. Specific system objectives Identify the health services that are offered in the neighborhoods that can be found in the region of the analysis to be able to get baseline data. Raise the insurance of women that are Fgf2 pregnant that obtain checkups regarding to appropriate wellness procedures to 100%. Identify and deal with attacks by HIV, syphilis, HBV, and ChD in women that are Levobupivacaine pregnant and newborns Identify risky being pregnant for follow-up and eventual recommendation to more technical wellness centers, simply because needed Raise the true variety of institutional births in the neighborhoods that reside in the involvement region. Optimize monitoring and follow-up of the grade of maternal-child wellness attention by using quality software to boost clinical management of these contained in the plan. Evaluate efficacy from the sanitary involvement model suggested. Characteristics of regions of the Americas with dispersed rural populations that require to be Levobupivacaine looked at for execution Geographic and climatic features.

The framework for the elimination of mother-to-child transmission (EMTCT Plus) was proposed by the Pan American Health Business in 2017 to all member states in order to widen the already existing framework for HIV and syphilis to include elimination of the infection with hepatitis B virus (HBV) and Chagas disease (ChD), now called EMTCT Plus