We present that tumor reprogramming of hematopoiesis in bone marrow occurs at the onset of malignant conversion and results in systemic expansion of circulating activated neutrophils that preferentially accumulate in lungs. Fig. S4 and and Fig. S4 and and and…
The cancer stem cell (CSC) model suggests that a small subpopulation
The cancer stem cell (CSC) model suggests that a small subpopulation of cancer cells possesses the ability to self-renew and give rise to malignant progeny that drive cancer progression. (Offers2) transgenic mouse model shown that hyaluronan overproduction caused rapid development…
Background Epithelial cells of developing embryonic organs such as salivary glands
Background Epithelial cells of developing embryonic organs such as salivary glands can display substantial motility during branching morphogenesis. rate of migration was stimulated by inhibiting E-cadherin. Conclusions Cell motility in developing salivary glands was highest in cells in contact with…