Supplementary MaterialsSupplemental data jciinsight-3-120274-s090. associated with advanced fibrosis, as exemplified by those encoding the transcription factor ETS-homologous factor (mRNA levels were also elevated in murine CLD models. We thus reveal a common gene signature for CLD-associated liver fibrosis and potential…
The activation of pro-inflammatory gene programs by nuclear factor-κB (NF-κB) is
The activation of pro-inflammatory gene programs by nuclear factor-κB (NF-κB) is primarily regulated through cytoplasmic sequestration of NF-κB from the inhibitor of κB (IκB) CYC116 category of proteins1. reduced amount of TNFα in response to lipopolysaccharide (LPS) despite the fact…