Introduction Toll-like receptors (TLRs) are a family of receptors that sense pathogen associated patterns such as bacterial cell wall proteins. antibodies (ANCA) associated vasculitides (AAV) are a group of severe autoimmune disorders, characterized by necrotizing inflammation of small- to medium-sized…
Eukaryotic initiation factor 2B (eIF2B) a five subunit guanine nucleotide exchange
Eukaryotic initiation factor 2B (eIF2B) a five subunit guanine nucleotide exchange factor (GEF) plays a key role in the regulation of mRNA translation. expression was accompanied by reductions in GEF activity and global rates of protein synthesis. Moreover repressed eIF2Bε…