Background Chronic myeloid leukemia (CML) is definitely driven from the fusion kinase Bcr-Abl. up- and downstream of Gab2. Summary We demonstrate that SF and AX display potency in a variety of and mechanistically unique situations of TKI level of resistance,…
Background HIV-1 infected macrophages play a key role in HIV-1 infection.
Background HIV-1 infected macrophages play a key role in HIV-1 infection. upon differentiation of monocytes into macrophages which corresponds to the increased susceptibility of mature macrophages to HIV-1. In parallel expression of microRNA miR-145-5p predicted to target PDE8A mRNA strongly…