Toll-like receptors (TLRs) recognize microbial/viral-derived elements that trigger innate immune response and conflicting data implicate TLR agonists in cancer, either as protumor or antitumor brokers. HIF-1 expression in different prostate tumor cell lines underlie their differential response to TLR3 account…
Background Hypoxia Inducible Factor-1α (HIF-1α) manifestation in breast malignancy is associated
Background Hypoxia Inducible Factor-1α (HIF-1α) manifestation in breast malignancy is associated with a poor clinical outcome. were stained by immunohistochemistry for FIH-1 HIF-1α glucose transporter 1 (GLUT-1) and carbonic anhydrase IX (CAIX). Results 45 instances overexpressed HIF-1α 5 of which…