Background Fibroblasts play important tasks in several cancers. expression of PN was observed in tissues of benign liver disease and hepatocellular TAK-438 carcinoma. CCA patients with high levels of PN had significantly shorter survival time than those with low levels…
The role of Rho family GTPases in controlling the actin cytoskeleton
The role of Rho family GTPases in controlling the actin cytoskeleton and thereby regulating cell migration has been well studied for cells migrating on 2D surfaces. pore size and topography. Recently we exhibited that collagen alignment accompanies tumor progression and…
Autophagy is an important stress response pathway responsible for the removal
Autophagy is an important stress response pathway responsible for the removal and recycling of damaged or redundant cytosolic constituents. of autophagosome expansion during starvation. Screens also identified phosphatidyl ethanolamine methyl transferase (PEMT) and the IP3-receptors (IP3Rs) as mediators of Parkin-induced…